Siddaganga Institute of Technology,

Tumakuru

Autonomous Institute affiliated to Visvesvaraya Technological University, Belagavi

Siddaganga Institute of Technology,Tumakuru

Autonomous Institute affiliated to Visvesvaraya Technological University, Belagavi

Siddaganga Institute of Technology, Tumakuru

Autonomous Institute affiliated to Visvesvaraya Technological University, Belagavi

Siddaganga Institute of Technology, Tumakuru

Autonomous Institute affiliated to Visvesvaraya Technological University, Belagavi

Go Green

Center Of Excellence

Bio-INvENT Center of Excellence
SIT Tumakuru  ·  Established 2023  ·  DBT, Govt. of India

Bio-INvENT Center of Excellence

Ideation, design, development, testing and commercialization of innovative biomedical products — at the interface of biology, engineering and nanotechnology.

Cancer Biology 3D Bioprinting Nanomedicine Ocular Research Microfluidics Stem Cell Biology
₹5+Cr
Total Funding
15
Research Areas
17
Collaborators
22
Instruments

Vision & Mission

Our Vision

To become a world-class Center of Excellence in biomedical research, innovation and entrepreneurship.

Our Mission
  • Establish a state-of-the-art biomedical research infrastructure
  • Train and create future leaders in biomedical research and innovation
  • Provide affordable and high-efficiency biomedical products to the healthcare sector

Bio-INvENT CoE works at the interface of biology, medicine, chemical engineering, materials, nanotechnology and physics — conducting cutting-edge basic research in cancer biology, stem cell biology and ocular diseases, leading to the identification of unmet needs and development of engineering-driven biomedical solutions.

Focus Areas

01

Cancer Stem Cell Biology, Immunology & Immunotherapy

02

3D Bioprinting for Model Development — Cancer, Cornea & Skin

03

Cell-based Active Targeted Drug Delivery

04

Redox Biology & Nanomedicine

05

Corneal Pathophysiology & Pharmacology

06

AI-based Corneal Image Processing to Predict Treatment Outcomes

07

Nanomedicine to Tackle Corneal Storage & Transplant Rejection

08

Stimuli-responsive Drug Delivery to Treat Uveitis of the Eye

09

Ocular Surface Microenvironment Biosensing

10

Nongenetic Engineering of Mesenchymal Stem Cell

11

Plasma Activated Water-mediated Cancer Therapy

12

Nanoliposomes for Delivery of Nanomedicine & Therapeutics

13

COMSOL-based Simulation of Cell Lysis in Microfluidic Devices

14

Microfluidic Device for Generating Cell-based Nanovesicles

15

Microfluidic Device for Generating Liposome-coated Nanoparticles

Research Funding

₹5+ Crores
Total Research Funding Secured
  • Department of Biotechnology, Govt. of India2023 – 2027
    ₹3.36 Cr
  • Sree Siddaganga Education Society, Tumkur2017 – 2025
    ₹95 L
  • DST–SERB, Govt. of India2018 – 2021
    ₹35 L
  • Cutis Academy of Cutaneous Sciences2026 – 2027
    ₹34 L
  • Board of Research for Nuclear Sciences, Govt. of India2018 – 2021
    ₹29 L
  • Vision Group on Science & Technology, Govt. of Karnataka2020 – 2022
    ₹25 L
  • Association for Research in Vision Science & Ophthalmology, USA2022
    ₹7.5 L
  • SigmaXi & National Academy of Sciences, USA2024 & 2025
    ₹5.22 L
  • DST-Lockheed Martin-Tata Trusts2019
    ₹10 L
  • Cutis Medi Apparels LLP2026 – 2027
    ₹9 L
  • Indo-French Centre for Promotion of Advanced Research2016
    ₹2 L

Global Collaborators

International
National
Prof. S P Srinivas
Indiana University School of Optometry, Bloomington, IN, USA
Prof. Joseph Bonanno
Indiana University School of Optometry, Bloomington, IN, USA
Dr. Nitin Joshi
Harvard Medical School, Boston MA, USA
Dr. Jeffrey Karp
Harvard-MIT Health Sciences Technology Division, Cambridge, MA, USA
Dr. Arghya Paul
University of Western Ontario, Ontario, Canada
Dr. Chi-Hwa Wang
National University of Singapore, Singapore
Prof. William B Krantz
University of Colorado, Boulder
Dr. Mohan Verma
IIT Delhi
Dr. Suhanya Duraiswamy
IIT Hyderabad
Dr. Raju K Gupta
IIT Kanpur
Dr. Dharitri Rath
IIT Jammu
Dr. Abhijit Majumder
IIT Bombay
Dr. Lakshminarayana Rao
Indian Institute of Science (IISc), Bangalore
Dr. Santosh K Sandur
Bhabha Atomic Research Center (BARC), Mumbai
Dr. Nandakumar D N
NIMHANS, Bengaluru
Dr. Prema Padmanabhan
Sankara Nethralaya, Chennai
Dr. B S Chandrashekhar
Cutis Hospital, Bengaluru

Equipment & Instruments

E-01
Vertical Autoclave
Aspire Inc
E-02
Analytical Microbalance
Shimadzu
E-03
Automatic Ice Flaker
Labman Scientific
E-04
−20°C Freezer
Celfrost, USA
E-05
−80°C Freezer
PHCBI, Panasonic
E-06
Biosafety Cabinet Class II
Kewaunee, Japan
E-07
CO₂ Incubator
PHCBI, Panasonic
E-08
3D Bioprinter
Alfatek Systems (Anga Pro)
E-09
Chemidoc Imaging System
UVITech, UK
E-10
Microplate Reader
Thermo Scientific, USA
E-11
Inverted Fluorescence Microscope
Zeiss Axiovert 5, Germany
E-12
Laboratory Refrigerator
Celfrost, USA
E-13
pH Meter
EUTECH
E-14
Centrifuge
Eppendorf
E-15
Centrifuge
Remi Inc
E-16
Ultrasonic Waterbath
Labman Scientific
E-17
Vortex Mixer
GeNei
E-18
Cold Room
Bluecold
E-19
Optical Microscope
Labomed
E-20
Quantitative PCR
HiMedia
E-21
Hot Air Oven
Aspire Inc
E-22
Liquid Nitrogen Container
Thermo Scientific

Research Facilities

Class II Mammalian Cell Culture Facility
High Resolution Bioimaging Facility (Zeiss Axiovert 5)
Protein / DNA / RNA Quantification Facility (UVITech ChemiDoc)
Quantitative PCR Facility (HiMedia)
Biochemical Assay Facility (Microplate Reader)
Cell & Molecular Biology Facility — DNA/RNA & Protein Isolation
3D Bioprinting Facility (Alfatek Anga Pro Bioprinter)
Optical Microscope for Cell Visualization (LaboMed)
Freezer Facility — Liquid N₂, −80°C and −20°C
Nanobioengineering Facility — Probe Sonicator, Rotary Vacuum Evaporator

Industry Consultancy

Cutis Academy of Cutaneous Sciences

Protocol development for melanocyte isolation and purification for autologous transplantation in vitiligo patients.

Cutis Medi Apparels LLP

Fabrics functionalized with Carbon Quantum Dot–stabilized nanoparticles for advanced textile applications.

Ongoing & Completed Projects

  • Development, Optimization, and Antifungal Evaluation of Fabrics Functionalized with Carbon Quantum Dot–stabilized Nanoparticles for Textile Applications

  • Development and standardization of protocols for isolation, culture, characterization and purification of autologous melanocytes for transplantation in Indian vitiligo patients

  • Optimization and cost analysis of silver nanoparticles synthesis process for antimicrobial textile application

  • Investigation of the protective effects of AMPK activation against energy stress in cold-stored ex vivo donor corneal endothelium

  • Network center for research on glioblastoma stem cell-targeted T-Cell immunotherapy using non-genetically engineered mesenchymal stromal cells

  • Investigation of ferroptosis as the mechanism of hypothermia-induced cell death and barrier dysfunction in cold stored ex vivo corneal endothelium

  • Rescuing the hypothermia- and cytokine-induced damage to donor corneal endothelial functions by pre-treatment with microtubule stabilizers

  • Unraveling a new strategy of inhibition of Cholesteryl ester transfer protein by small molecule inhibitors through site directed mutagenesis and molecular dynamics simulation studies

  • CLeONs: High efficiency contact lens-coated oxygen nanosensors for eye clinics

  • Nanoparticle-based prophylactic drug delivery to the corneal endothelium

Faculty In-charge

SR
Dr. Sudhir H Ranganath
Associate Professor & Founder — Bio-INvENT CoE
Department of Chemical Engineering
Siddaganga Institute of Technology, Tumakuru, Karnataka

⁠⁠Photographs

Research — Center of Applied Research and Nanotechnology

Siddaganga Institute of Technology · CARN

Research in Nanotechnology

Advancing frontiers in nanomaterials, nanoelectronics, and nanomedicine to solve critical national challenges in energy, defence, health, and infrastructure.

The Center of Applied Research and Nanotechnology (CARN) has streamlined its R&D activities along three core pillars — nanomaterials, nanoelectronics, and nanomedicine — working towards tangible solutions for the nation's most pressing challenges.

Nanomaterials
Nanoelectronics
Nanomedicine
Diagnostics & Biosensing
Renewable Energy

01 · MATERIALS

Advanced Nano-materials

Developing nano-materials for flexible electronics, solar cells, solar collectors, solid-state displays, RF and millimetre wave communications.

02 · SMART STRUCTURES

Shape Memory Alloys

Research into shape memory alloys and smart structural materials for adaptive engineering applications and next-generation infrastructure.

03 · DEFENCE

Liquid Armor Composites

Engineering nano-composite materials for liquid armor systems, contributing to lighter and more effective personal and vehicle protection.

04 · ENERGY

Solar Renewable Energy

Materials and device research for solar renewable energy technology, including inorganic and organic semiconductors for photovoltaics.

05 · ELECTRONICS

GaN-based High-Power Devices

Gallium Nitride based devices engineered for high power and high frequency applications, pushing the limits of power electronics.

06 · RF SYSTEMS

Passive RF Devices & Circuits

Design and development of passive RF devices, thin-film sensors, MEMS and NEMS for next-generation communication and sensing systems.

07 · HEALTH

Affordable Diagnostic Devices

Development of affordable diagnostic and screening devices for clinical samples, improving healthcare access across India.

08 · FOOD SAFETY

Pesticide Detection Methods

Novel detection method development for pesticide safety assessment in food and agricultural commodities using nano-biosensors.

09 · AYURVEDA & MATERIALS

Herbal Bhasma & High-Purity Crystals

Standardization of Ayurvedic herbal-bhasma and development of monocrystalline high-purity alumina and silicon for electronic chip fabrication.

  • Affordable diagnostic devices and screening development for clinical samples
  • Detection method development for pesticide safety in food and agricultural commodities
  • Standardization of Ayurvedic herbal-bhasma for viral and bacterial infections
  • Development of monocrystalline high-purity alumina and silicon for electronic chip fabrication
  • Nano-bio sensors and nanobiotechnology for point-of-care diagnostics
  • Advanced thin-film sensors for environmental and biomedical monitoring
1Nano-electronics & Nano-photonics
2Nano-systems, MEMS & NEMS
3Nano-bio Sensors & Nanobiotechnology
4Advanced Nano-materials
5Nanotechnology Education & Outreach

Collaborate with Us

Interested in partnering on research, joint projects, or sponsored work?

Contact the Head, Center of Applied Research and Nanotechnology

Siddaganga Institute of Technology, Tumakuru

Email: hodnano@sit.ac.in

Get in Touch

© 2024 Center of Applied Research and Nanotechnology (CARN) · Siddaganga Institute of Technology, Tumakuru, Karnataka

MNC TE CARE — Centre for Transformative Engineering
Dept. of Mechanical Engineering  ·  SIT Tumakuru
MNC TE CARE

M N Channabasappa Centre
for Transformative Engineering
in Circular Materials,
Additive Manufacturing,
Research & Education

Fostering advancements in polymer science focused on sustainable materials — addressing environmental challenges through innovative materials, sustainable manufacturing practices, and cutting-edge additive manufacturing technologies.

₹102L
Project Cost
3
Key Objectives
3
Research Areas
3+
Equipment

About the Centre

The Multifunctional Polymer Research and Training Centre aims to foster advancements in polymer science, focused on sustainable materials. The centre addresses environmental challenges through the development of innovative materials, sustainable manufacturing practices, and cutting-edge additive manufacturing technologies.

Core Objectives

🌿
Environmental Solutions

Develop sustainable polymers and manufacturing practices that minimise environmental impact, driving circular material strategies for a greener future.

🖨️
Additive Manufacturing

Advance the capabilities and applications of 3D printing and other additive manufacturing techniques using high-performance polymers for diverse industrial needs.

⚗️
Material Innovation

Create novel multifunctional polymers with enhanced properties for diverse industrial applications, pushing the boundaries of what modern materials can achieve.

Key Research Areas

01 Sustainable Polymers
SP-01

Recyclable polymers — design, processing and end-of-life recovery strategies

SP-02

Life cycle analysis of polymer products for environmental impact assessment

02 Advanced Additive Manufacturing
AM-01

Development of polymer-based 3D printing materials with improved performance

AM-02

Optimization of additive manufacturing processes for enhanced structural performance

AM-03

Integration of nanotechnology in additive manufacturing for functional enhancements

03 High-Performance Materials
HP-01

High-strength, lightweight polymers for structural and aerospace applications

HP-02

Functional polymers and polymer composites with improved sustainability profiles

Training & Education

🎓
Program 01
Workshops

Targeted workshops designed to disseminate knowledge and foster collaboration among researchers and students — bridging the gap between academic research and industrial application in polymer science and additive manufacturing.

🔬
Program 02
Hands-on Projects

Practical, hands-on projects integrated into training programs, allowing participants to work on real-world challenges in polymer materials — from ideation and material selection through prototyping and performance testing.

Equipment & Instruments

E — 01
Differential Scanning Calorimeter
PerkinElmer · Pyris DSC 9
Category
Thermal Analysis Instrument with Intra Cooler
Temp. Range
−70°C to 750°C
Heating Rate
0.01°C/min to 100°C/min
Make / Model
PerkinElmer / Pyris DSC 9
E — 02
Melt Flow Index Tester
Pacorr · CAMFIC-1
Category
Computerised MFI (CAMFIC-1)
Temp. Range
Up to 400°C
Standards
ISO 1133 & ASTM D 1238
Make
Pacorr Testing Instruments
E — 03
Granulator
Polymer Processing Equipment
Motor Power
0.37 kW, 50 Hz
Rotating Speed
26 rpm, 50 Hz
Teeth Cutter
Material: SKD11 · Staggered: 2 · Teeth: 3
Cutting Chamber
140 × 175 mm

Lab Space

Lab Inauguration

Principal Investigator

MH
Dr. Madhu H C
Principal Investigator & Centre In-charge
Assistant Professor
Department of Mechanical Engineering
Siddaganga Institute of Technology, Tumakuru
Project Cost
₹102
Lakhs
Chemistry Research Centre — SIT Tumakuru
01 — Objectives

Centre Objectives

01
🔬
Advanced Research & Innovation

Promote advanced research and innovation in diverse areas of chemistry such as materials chemistry, energy storage, catalysis, environmental remediation, and nanotechnology to address contemporary scientific and societal challenges.

02
🤝
Interdisciplinary Collaboration

Facilitate interdisciplinary collaboration among chemists, physicists, biologists, and engineers to develop sustainable technologies, advanced functional materials, and efficient chemical processes.

03
🎓
Training & Capacity Building

Support training and capacity building by providing research infrastructure, mentorship, and skill development opportunities for students, scholars, and faculty to enhance scientific excellence and knowledge dissemination.

02 — Activities

Workshops & Events

  • 01
    Two Days Workshop on Characterization Techniques for Nanomaterials and Applications to Lithium Ion Battery (CTNALB-2017)
    March 10–11, 2017
    2-Day
  • 02
    One Day Workshop on "Analytical Techniques in Nanotechnology"
    May 21, 2024 — Tuesday
    1-Day
  • 03
    One Day Workshop on "Hands on demonstration on synthesis of nanomaterials and its characterization"
    January 09, 2025
    1-Day
  • 04
    One Day Workshop on "Crystal structure analysis using X-ray diffraction technique"
    May 03, 2025
    1-Day
  • 05
    Four Week Training Programme on "Synthesis of metal oxide nanomaterials and its characterization techniques"
    April 02, 2025 — May 01, 2025
    4-Week
  • 06
    One Day Workshop on "Characterization of nanomaterials using XRD"
    July 02, 2025
    1-Day
03 — Facilities

Equipment & Facilities

No. Equipment Funding Agency
01 X-Ray Diffraction (XRD) DST-Nanomission
02 Spectrofluorimeter DST-Nanomission
03 UV-Visible Spectrophotometer DST-Nanomission
04 HPLC (High Performance Liquid Chromatography) DST-Nanomission
05 Battery Testing Unit DST-SERB
06 FTIR Spectrometer SIT, Tumakuru
07 Electrochemical Workstation (CH Instruments) SIT, Tumakuru
08 Atomic Absorption Spectrometer (AAS) TEQIP Grant, SIT Tumakuru
09 Rotavapour ISRO-RESPOND
10 UV and Visible Source Photoreactor VGST-SMYSR
11 Sputtering Unit DST
11
Total Equipment
6
Funding Agencies
4
DST-Nanomission
2
SIT Funded
Department of Chemistry · Siddaganga Institute of Technology, Tumakuru
Materials Chemistry · Energy Storage · Catalysis · Environmental Remediation · Nanotechnology